Corneal cross-linking is a surgical procedure developed in Germany in 2003. It involves application of riboflavin (vitamin B2) solution to the eye that is activated by illumination with UV-A light for approximately 30 or fewer minutes. The riboflavin causes new bonds to form across adjacent collagen strands and proteoglycans in the stromal layer of the cornea, which recovers and preserves some of the cornea’s mechanical strength. This increases the strength of the cornea and allows it to retain its current corneal shape. Since it has been confirmed that the progression of keratoconus stops in over 90% of people, it is regarded as the standard treatment for early keratoconus in Europe and the United States.
If keratoconus us detected early, this is the first treatment you should take. From the age of 14 years, you can receive treatment at our hospital with the understanding of the treatment method and the consent of the parent or guardian.
●Individuals over 14 years old
●Those who have been diagnosed with progressive keratoconus or corneal keratectasia after corneal refraction correction
●Those with the thinnest cornea thickness of 400μm or more
●Those with eye diseases (active infections, history of corneal herpes, glaucoma, retinal degenerative diseases, etc.)
●Those with a history of corneal transplantation, glaucoma surgery, retinal detachment surgery, etc.
●Those with systemic diseases that affect corneal wound healing, such as collagen disease
●Those who are pregnant and lactating
●Those not suitable for surgery as judged by doctor
The latest mosaic system, which will be introduced for the fourth time in Japan, is topography-guided accelerated cross-linking, which can efficiently irradiate ultraviolet rays according to the protrusion of keratoconus because of the shape of the cornea.
Compared with conventional equipment, less follow-up reduced operation time of approximately 30min is required for this treatment. Postoperative pain is also significantly reduced because it can be treated without removing the corneal epithelium. In addition to suppressing the progression of keratoconus, mild flattening of the cornea can reduce the degree of myopia and astigmatism.
For the purpose of strengthening the cornea, we don’t recommend topography-guided accelerated cross-linking to those who are not keratoconus.
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